Our Pharmaceutical Wastewater Solution

Pharmaceutical wastewater is rarely predictable. Even where a site already has biological treatment, RO membranes, or other established processes in place, trace residuals can remain.

Arvia understands these pressures because we work directly with pharmaceutical companies and biopharma sites facing persistent organic contaminants in their effluent. Our patented Nyex™ technology combines adsorption with electrochemical oxidation, supporting trace-level removal without chemical dosing and without the need for media replacement through in-situ regeneration.

Our advanced water treatment systems are designed for exactly this tertiary water treatment role. Our technology is proven, demonstrating significant success within pharmaceutical industries, where wastewater often contains complex organic compounds that standard treatment routes struggle to address.

Arvia Technology is a global leader in Wastewater Treatment for the Pharma industry. Talk to a specialist today.

03.30.2023

CASE STUDY: Removal of Pharmaceutical Residues and APIs

A comprehensive removal of APIs of >90% and often to below LOD (the limit of detection).

Wastewater Treatment Services for Pharma Manufacturing industries

Removal of Organic Compounds

We specialise in removing several organic compounds associated with Pharma industries such as: APIs, antibiotics, steroids, hormones, EDCs and banned organic chemicals. We also specialise in COD polishing to low levels.

Water Reuse

Our water treatment systems are designed to remove persistent chemicals that other technologies may leave behind. An essential polishing step as part of your Zero Liquid Discharge strategy.

Blowdown water treatment

Your blowdown water treatment might leave behind recalcitrant organic chemicals or not reduce COD to low enough levels for reuse. Ask us how our specialist systems can complement your treatment systems.

Why choose a Nyex water treatment process?

Our Nyex water treatment systems are used for tertiary wastewater polishing or for removing specific organic compounds. In terms of pharmaceutical wastewater treatment, we can remove APIs, antibiotics, hormones, steroids and EDCs, as well as surfactants, corrosion inhibitors and biocides to very low levels. This makes them very suitable for use in life sciences companies which manufacture pharmaceuticals or APIs and require removal of hazardous compounds to below the contaminant’s Predicted No Effect Concentration (PNEC).

Our Nyex water treatment processes have been designed to tackle the wastewater issues faced by the life sciences sectors, with these key benefits:

  1. Cost Effective: Our systems negate the need for the inefficient and expensive incineration of wash water or hazardous compounds.
  2. Treatment of APIs: Low energy and targeted treatment of APIs, antibiotics, steroids, hormones and EDCs enabled by Arvia’s unique combination of adsorption and electrochemical oxidation.
  3. Eco Friendly Process: Our systems are effective without hazardous chemical dosing and subsequently there are no solid waste products.
  4. Improve Existing Processes: Improve efficiencies and reliability of existing treatment processes by removing fouling organics and hazardous organic chemicals at key points in the chain.
  5. Modular System: Flexible and modular systems can be turned on and off according to demand, meeting variable loading over time and accommodating future expansion.
  6. Containerised or skid mounted plants: All our systems are bespoke to your needs following treatability trials and pilot scoping. Our containerised plants can be positioned outside and our skid mounted plants can be integrated onsite to fit with your site requirements.

A Different Approach

Nyex™ — Adsorption & Electrochemical Oxidation

Unlike conventional methods, the Nyex process combines adsorption with in-situ electrochemical destruction. Contaminants are concentrated onto the media surface then destroyed — not transferred to another waste stream. The media regenerates continuously, eliminating the saturate-replace cycle.

See how it works.

How Nyex works: Adsorption and Electrochemical Oxidation

The Nyex™ process uses Arvia’s proprietary conductive media to attract and concentrate persistent pharmaceutical compounds onto its surface. Once adsorbed, these organics are destroyed in situ through electrochemical oxidation, breaking down APIs and other recalcitrant contaminants rather than transferring them into a secondary waste stream.

1

Adsorption

Recalcitrant organic contaminants such as APIs and other persistent pharmaceutical compounds are selectively adsorbed onto the Nyex™ media surface, concentrating them from the bulk water phase. This step is particularly effective at low influent concentrations, where conventional treatment technologies can struggle to achieve stable removal.

2

Electrochemical Oxidation

A low-voltage current is applied, oxidising the adsorbed compounds directly on the media surface. This destroys the target organics in situ, breaking them down into simpler, non-hazardous by-products rather than transferring them into another waste stream.

3

In-Situ Regeneration

The oxidation step simultaneously regenerates the media surface, restoring its adsorption capacity during operation. This removes the need for frequent media replacement, off-site regeneration or secondary waste disposal, giving pharmaceutical manufacturers a more practical, low-carbon and operationally simple alternative to conventional adsorption systems.

Our pharmaceutical wastewater treatment technologies use a patented combination of adsorption and electrochemical oxidation.

Position in the Treatment Train

The Nyex system is typically deployed as a tertiary polishing step after biological treatment, targeting the residual colour that conventional processes leave behind. It can also be used for targeted pre-treatment to protect downstream membranes or stabilise sensitive processes.

Pre-treatment

Upstream Process

Screening, pH adjustment, primary settlement and flow balancing

Biological Treatment

Biological Stage

Reduction of bulk BOD and COD, while persistent pharmaceutical compounds may remain

Nyex™ Treatment

Arvia Solution

Adsorption and electrochemical oxidation to remove APIs and other recalcitrant organics

Compliant Discharge

Output

High-quality effluent suitable for discharge compliance or onward reuse objectives

Test, Pilot, Scale – Proving efficacy

1

Treatability trial

We test on a sample of your wastewater to confirm which of our technologies is the most effective match for your specific matrix. The treatability trials establish removal performance, and provide the data needed for informed decision-making. We typically need 20–50 litres of effluent for pollutant removal, COD reduction, and any contaminants of interest.

2

Pilot testing

Our technicians work with your process team to install a pilot plant to assess performance under real operating conditions, including variability in flow, load, and temperature, and confirm scale-up assumptions. Pilots typically run for 4–12 weeks depending on variability. This stage validates operability, maintenance requirements, and confirms design parameters for the full-scale system.

3

Full scale deployment

Modular, factory-built systems are delivered, installed, and commissioned with full technical support. Ongoing monitoring and support ensures sustained performance. Systems are designed for retrofitting into existing treatment trains. Commissioning includes operator training, documented procedures, and a defined support package.

Jerome Budin

Wastewater consultant

Schedule a trial with our experts to find out how we can help you remove colours from your wastewater.