Triton X-100

Triton X-100 (TX-100) is a non-ionic surfactant with various uses in the pharmaceutical industry, including for cleaning and as an ingredient in some medicinal products.

Removal of Triton X-100 from Pharmaceutical Wastewater is now on the agenda because, due to potential endocrine disrupting properties, the substance has been placed into Annex XIV of the REACH regulation. This means that it cannot be used or placed on the market after the “sunset date” which is 4th January 2021 unless an exemption certificate is held. Those with the certificate need to entirely remove Triton X-100 from wastewater to comply.

This regulatory amend has forced users of Triton X-100 to investigate options to fully remove it from wastewater to prevent its release into the sewer or aquatic environment.

A method currently adopted for the management of contaminated water is thermal oxidation. This process involves the water being collected and trucked off to a third-party specialist to be incinerated – a very expensive process with negative environmental implications.

This has led to pharmaceutical facilities looking for onsite wastewater treatment alternatives which are lower maintenance, as well as more cost-effective and sustainable.

Additional benefits for onsite treatment include complete traceability of hazardous waste for audit purposes and retaining complete control over compliance with upcoming legislation.

The Triton X-100 Project

The aim of this project was to study the ability of the Nyex™-e system to destroy Triton X-100 from an aqueous solution to as low concentration as possible.

Oxidation experiments were conducted using a Nyex™-e to evaluate its effectiveness in destroying the Triton X-100.

HPLC and LCMS analysis was carried out on each sample to determine the concentrations of Triton X-100, starting from 16 mg/L. Experiments were conducted in a re-circulation mode and sampled from the container.

The Solution: Removal of Triton X-100 from water

Arvia’s Nyex™-e system was deployed against this application. This process uses electrochemical oxidation in a single, scalable unit. A low electrical current is passed which fully mineralises the contaminants to H₂O, H₂ and CO₂.

Results are achieved without chemical dosing or the generation of sludge reducing costs in terms of labour, transport of chemicals and specialist waste disposal.